Light-activated electrolyte oxidizes water to promote tumor cell death

Apr, Fri, 2026
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A research team led by Professor Jin Yong Lee from the Department of Chemistry of Sungkyunkwan University, with co-first author HyoungChul Ham, and in collaboration with research teams from Korea University and the National University of Singapore, has developed a next-generation phototherapeutic agent, “NDI-COE.” This agent induces pyroptosis (inflammatory cell death) in hypoxic tumor tissues by directly oxidizing intracellular water.

Light-activated electrolyte oxidizes water to promote tumor cell death
A research team led by Professor Jin Yong Lee from the Department of Chemistry of Sungkyunkwan University, with co-first author HyoungChul Ham, and in collaboration with research teams from Korea University and the National University of Singapore, has developed a next-generation phototherapeutic agent, "NDI-COE." This agent induces pyroptosis (inflammatory cell death) in hypoxic tumor tissues by directly oxidizing intracellular water.
Waste biomass helps unlock hydrogen and formate in lower-energy electrolysis
A research team has developed a high-efficiency electrochemical system that simultaneously produces hydrogen and value-added chemicals using glycerol, a low-cost, abundant byproduct of biodiesel production. The findings are published in Joule.
DNA damage just got more complicated: A long-missed weak spot emerges when light and oxygen strike
In everyday life, our genetic material is constantly under attack from many factors. Environmental influences such as light, along with internal processes like inflammation, can generate oxidative stress that damages DNA and its downstream partner, RNA, which can lead to faster aging and diseases such as cancer.
Atomic-level snapshots reveal how a key copper enzyme powers nature's chemistry
Researchers from the University of Liverpool, Japan, and Argentina have captured atomic-resolution images of an important copper-containing enzyme using advanced X-ray Free Electron Laser (XFEL) technology at SACLA in Japan. XFEL technology generates ultra-bright, ultra-short X-ray pulses, enabling atomic-scale imaging and real-time observation of chemical, biological, and physical processes.
Apple byproducts could power vehicles and feed livestock
A new study published in Biofuels, Bioproducts and Biorefining highlights an innovative approach to transforming apple pomace—an often-discarded by-product of apple processing—into valuable bioethanol and animal feed ingredients. Apple pomace, which represents 25%–30% of processed apples, is typically treated as waste despite its rich carbohydrate content and strong potential for bioconversion.