Feeding data to AI to speed up drug discovery

Jun, Mon, 2026
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Developing new medicines can require thousands of chemistry experiments to identify the right recipe for a safe, effective and ideally affordable drug.

Feeding data to AI to speed up drug discovery
Developing new medicines can require thousands of chemistry experiments to identify the right recipe for a safe, effective and ideally affordable drug.
How oxygen sneaks into a corked wine bottle long before the first pour
The main reason for sealing wine bottles with a cork is to protect the liquid from oxygen. However, it is not an impermeable barrier, and a small amount of air leaks in, which is not always entirely bad news. The gas helps the wine mature and develop a more complex flavor.
Faster aptamer screening finds synthetic alternatives to antibodies in days instead of months
Aptamers are short DNA or RNA strands that can recognize and bind to a specific target molecule with high precision. Similar to antibodies, they can be used to detect these molecules or modulate their activity. Unlike antibodies, they are much more stable, can be produced synthetically and can be chemically modified to achieve the desired properties. As a result, they can offer capabilities that cannot be achieved with antibodies.
Brain enzyme caught doing something unexpected—it builds polysialic acid on itself
A chance discovery at Nagoya University in Japan has shown that a well-known brain enzyme has a hidden ability: It builds a sugar chain on itself, becomes secreted from the cell and deactivates, then switches on outside the cell once the chain is removed. The finding, published in the Journal of Biological Chemistry, overturns a decades-old assumption about how polysialic acid, a sugar chain critical for brain development and function, is produced and shows a new way an enzyme can regulate its own activity.
Trace additive unlocks faster bioplastic biodegradation without losing transparency or strength
Compostable plastics could be part of a solution to the world's plastic waste problem. But currently these materials need industrial composting facilities to break down. In a step toward making a home-compostable plastic, researchers reporting in ACS Central Science have augmented polylactide (PLA)—a widely used biobased and compostable polymer—with a small amount of an additive. Tests show it helps the material degrade substantially faster without sacrificing critical qualities like strength or transparency.