Ribosome-based gene circuit lets cells read six signals and trigger responses

Jul, Sat, 2026
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The molecular machinery that normally builds proteins inside cells has now taken on a new role as a “switch.” A research team at POSTECH (Pohang University of Science and Technology) has developed a new ‘RNA-based smart gene circuit’ platform that can simultaneously read multiple signals inside a cell, make its own decisions and autonomously generate programmed responses. This represents a step beyond simple genetic manipulation toward an era in which cells themselves function as “living computers.”

Ribosome-based gene circuit lets cells read six signals and trigger responses
The molecular machinery that normally builds proteins inside cells has now taken on a new role as a "switch." A research team at POSTECH (Pohang University of Science and Technology) has developed a new 'RNA-based smart gene circuit' platform that can simultaneously read multiple signals inside a cell, make its own decisions and autonomously generate programmed responses. This represents a step beyond simple genetic manipulation toward an era in which cells themselves function as "living computers."
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